I experience severe discomfort without any specific diagnosed diseases or injuries. When I take 6g of arginine jelly and a 200mg caffeine caplet, I feel completely fine after about 30 minutes. Does this make sense, or could it just be a placebo effect?
ChatGPT’s answer is:
This reaction can indeed make sense, as both L-arginine and caffeine can have physiological effects that might temporarily alleviate feelings of discomfort or low energy.
L-arginine Effects: Arginine is an amino acid that helps increase nitric oxide production, which can improve blood flow and enhance oxygen delivery to tissues. This process can lead to feelings of improved energy or reduced fatigue, which may contribute to your overall sense of relief.
Caffeine Effects: Caffeine is a central nervous system stimulant that can improve alertness, reduce perceived fatigue, and elevate mood temporarily. The 200mg dose is considered moderate and can boost energy levels, often providing relief if discomfort is related to low energy or mental fog.
Placebo Factor: While these effects are likely real and based on the substances’ mechanisms, the placebo effect could still play a role, especially if your body has come to expect relief from this combination. The mere anticipation of feeling better can amplify the effects, making the combination feel even more effective.
In summary, it’s plausible that both physiological effects and placebo may be contributing to the relief you experience.
metabolized to produce catecholamines such as dopamine (DA) and norepinephrine (NE) taken as a supplement to help increase catecholamine levels depleted during stressful or challenging conditions
used in the production of thyroid hormones
benefits
related to its ability to replenish catecholamine levels in the brain, which can become depleted under stressful conditions
Multiple studies have demonstrated that L-tyrosine can help to prevent declined cognitive function under stressful, cognitively demanding conditions
Although it has not been shown to improve memory under resting conditions, L-tyrosine supplementation has been shown to alleviate reduced memory under acutely stressful conditions.
Overall L-tyrosine appears to be safe and well-tolerated at moderate doses, with one 2-week human trial using a dose of 2500 mg, provided three times per day, and another trial using single doses of up to 150 mg/kg of body weight (around 10,000 mg for a 68 kg/150 lb individual), both with no adverse effects.
drawbacks
Although L-tyrosine has shown beneficial effects in some studies, it has a mixed track record for efficacy, with some studies failing to observe positive effects on cognition.
This may be partially explained by the fact that L-tyrosine increases catecholamine synthesis only when catecholamine levels are depleted, limiting efficacy to sufficiently stressful or challenging conditions. Efficacy may also vary in different individuals, as highlighted by one study that found that the effects of L-tyrosine on cognitive function become detrimental with older age.
There are also possible contraindications for L-tyrosine supplementation in people with hyperthyroidism or anyone taking L-dopa or monoamine oxidase inhibitors. If this applies to you, consult with your physician before supplementing with L-tyrosine.
works
used in the body to make the catecholamines dopamine (DA) and norepinephrine (NE), which can become depleted under stressful or cognitively challenging conditions.
After supplementation, L-tyrosine levels in the blood peak after one to two hours, and stay elevated for up to eight hours.
then passes through the blood-brain barrier, where it is absorbed by brain cells and converted in a series of enzymatic reactions to DA, which can be converted to NE through the action of another enzyme.
The ability of L-tyrosine to enhance catecholamine synthesis only in neurons that are actively firing may explain its ability to reverse the effects of neurotransmitter depletion during stress
dosage
tends to be taken in doses of 500–2000 mg approximately 30–60 minutes before any acute stressor (this tends to be exercise)
Studies in humans showing most anti-stress promise for acute supplemental L-Tyrosine use a dosage range of 100–150 mg/kg of bodyweight which can be taken 60 minutes before exercise; this is a dosage range of 9–13.5 g for a 200 lb person and 7–10 g for a 150 lb person.
If using higher doses and finding digestive issues, this may be split into two doses separated by half an hour (30 and 60 minutes prior to acute stress).
‘공먹젤 익스트림‘이 ‘공먹젤‘에 비해 더 가지고 있는 요소가 L-Tyrosine이어서 궁금해 확인
