L-Tyrosine

from https://examine.com/supplements/l-tyrosine


amino acid

metabolized to produce catecholamines such as dopamine (DA) and norepinephrine (NE)
taken as a supplement to help increase catecholamine levels depleted during stressful or challenging conditions

used in the production of thyroid hormones

benefits

related to its ability to replenish catecholamine levels in the brain,
which can become depleted under stressful conditions

Multiple studies have demonstrated
that L-tyrosine can help to prevent declined cognitive function under stressful, cognitively demanding conditions

Although it has not been shown to improve memory under resting conditions,
L-tyrosine supplementation has been shown to alleviate reduced memory under acutely stressful conditions.

Overall L-tyrosine appears to be safe and well-tolerated at moderate doses,
with one 2-week human trial using a dose of 2500 mg, provided three times per day,
and another trial using single doses of up to 150 mg/kg of body weight (around 10,000 mg for a 68 kg/150 lb individual),
both with no adverse effects.

drawbacks

Although L-tyrosine has shown beneficial effects in some studies,
it has a mixed track record for efficacy,
with some studies failing to observe positive effects on cognition.

This may be partially explained by the fact that L-tyrosine increases catecholamine synthesis only when catecholamine levels are depleted, limiting efficacy to sufficiently stressful or challenging conditions. Efficacy may also vary in different individuals, as highlighted by one study that found that the effects of L-tyrosine on cognitive function become detrimental with older age.

There are also possible contraindications for L-tyrosine supplementation in people with hyperthyroidism or anyone taking L-dopa or monoamine oxidase inhibitors. If this applies to you, consult with your physician before supplementing with L-tyrosine.

works

used in the body to make the catecholamines dopamine (DA) and norepinephrine (NE),
which can become depleted under stressful or cognitively challenging conditions.

After supplementation,
L-tyrosine levels in the blood peak after one to two hours,
and stay elevated for up to eight hours.

then passes through the blood-brain barrier,
where it is absorbed by brain cells and converted in a series of enzymatic reactions to DA,
which can be converted to NE through the action of another enzyme.

The ability of L-tyrosine to enhance catecholamine synthesis only in neurons that are actively firing
may explain its ability to reverse the effects of neurotransmitter depletion during stress

dosage

tends to be taken in doses of 500–2000 mg
approximately 30–60 minutes before any acute stressor (this tends to be exercise)

Studies in humans showing
most anti-stress promise for acute supplemental L-Tyrosine use a dosage range of 100–150 mg/kg of bodyweight which can be taken 60 minutes before exercise; this is a dosage range of 9–13.5 g for a 200 lb person and 7–10 g for a 150 lb person.

If using higher doses and finding digestive issues,
this may be split into two doses separated by half an hour (30 and 60 minutes prior to acute stress).


공먹젤 익스트림‘이 ‘공먹젤‘에 비해 더 가지고 있는 요소가 L-Tyrosine이어서 궁금해 확인

성분명(관심 성분만)공먹젤 익스트림공먹젤젤
L-arginine1,500mg1,400mg
L-tyrosine400mg
taurine1,000mg1.000mg
zinc3mg3mg
L-theanine200mg

L-theanine은 help reduce stress and anxiety. 100-400mg/day. 여유 있을 때 내용 추가할 수.